Flavor ingredient regulatory record

7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone

7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone is a ketone in the fruity family, FEMA GRAS under FEMA number 3715 (CAS 34545-88-5). Its odor is sweet, fruity, floral, woody, creamy.

FEMA
3715
CAS
34545-88-5
JECFA
1405
EU FL
07.136
Formula
C11H14O
EC
252-079-8

GRAS status: FEMA GRAS, publication 13. Recorded by FDA in the Substances Added to Food inventory under CAS 34545-88-5.

Structure

2D structure of 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone
Structure of 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone, C11H14O. Drawn from the canonical SMILES.

Identity

IUPAC name 7-methyl-4,4a,5,6-tetrahydro-3H-naphthalen-2-one
CAS number 34545-88-5
FEMA number 3715
Molecular formula C11H14O
Molecular weight 162.23 g/mol
SMILES CC1=CC2=CC(=O)CCC2CC1
InChIKey NGSXTBFUMNXJDK-UHFFFAOYSA-N
PubChem CID 61935
EC number 252-079-8
FDA UNII 4TIV4S045F
EPA DTXSID DTXSID90865721
Chemical class Ketone
Boiling point 138 °C
Flash point 53 °C

Also known as: 2(3H)-Naphthalenone, 4,4a,5,6-tetrahydro-7-methyl-, 4,4a,5,6-Tetrahydro-7-methyl-2(3H)-naphthalenone, NSC 75764, Kumarone, coconut naphthalenone, kumarone, 2(3h)-naphthalenone, 4,4a,5,6-tetrahydro-7-methyl-, 7-methyl-4,4a,5,6-tetrahydro-2(3h)-naphalenone, 4,4a,5,6-tetrahydro-7-methylnaphthalene-2(3h)-one, 4,4a,5,6-tetrahydro-7-methyl-2(3h)-naphthalenone, 7-methyl-4,4a,5,6-tetrahydro-2(3h)-naphthalenone [fhfi], (+-)-7-methyl-4,4a,5,6-tetrahydro-2(3h)-naphthalenone.

Can 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone be labeled natural?

The process decides for 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone is FEMA GRAS under FEMA number 3715. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 07.136, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1405, evaluated at the 63rd meeting in 2004. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, floral, woody, creamy.

Taste: Sweet, rich, smooth.

Where it is used

7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone is used in beverage, confection, flavoring, bakery and dairy, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Dehydromenthofurolactone375562%In nature
p-Menth-3-en-1-ol356361%In nature
p-Menth-1-en-9-al317858%In nature
p-Mentha-1,3-diene355857%In nature
Dehydronootkatone409157%In nature

More ketones in this index

2-Methoxyacetophenone · 4-Methylheptan-3-one · 2-Hepten-4-one · Methylcyclopentenolone · Acetoin · 9-Decen-2-one

7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone FAQ

Does 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone have FEMA GRAS status?

7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone holds FEMA GRAS status under FEMA number 3715. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone by FEMA or CAS number?

Cite 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone as FEMA 3715 or CAS 34545-88-5; both point to the same entry. Its flavor category is fruity.

What does 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone smell and taste like, and where is it used?

The odor of 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone is sweet, fruity, floral, woody, creamy. On the palate it is sweet, rich, smooth. Typical uses are beverage, confection, flavoring, bakery and dairy.

What did JECFA conclude about 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone?

JECFA evaluated 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone at the 63rd meeting in 2004 under JECFA number 1405. The panel concluded: no safety concern at current levels of intake.

Can 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone be used in the EU and UK?

Yes. FL 07.136 is the Union List entry for 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Can 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone be labeled a natural flavor?

Nature makes 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 7-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone identical-to-natural.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 7-METHYL-4,4A,5,6-TETRAHYDRO-2(3H)-NAPHTHALENONE under CAS 34545-88-5 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.