Flavor ingredient regulatory record

Cinnamyl butyrate

Cinnamyl butyrate is an ester in the fruity family, FEMA GRAS under FEMA number 2296 (CAS 103-61-7). Its odor is sweet, fruity, floral, buttery, tropical.

FEMA
2296
CAS
103-61-7
JECFA
652
EU FL
09.053
Formula
C13H16O2
EC
203-128-7

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 103-61-7.

Structure

2D structure of Cinnamyl butyrate
Structure of Cinnamyl butyrate, C13H16O2. Drawn from the canonical SMILES.

Identity

IUPAC name [(E)-3-phenylprop-2-enyl] butanoate
CAS number 103-61-7
FEMA number 2296
Molecular formula C13H16O2
Molecular weight 204.27 g/mol
SMILES CCCC(=O)OC/C=C/c1ccccc1
InChIKey YZYPQKZWNXANRB-UXBLZVDNSA-N
PubChem CID 5355254
EC number 203-128-7
Chemical class Ester
Boiling point 300 °C
Flash point 137 °C

Also known as: Butanoic acid, 3-phenyl-2-propen-1-yl ester, Butyric acid, cinnamyl ester, Butanoic acid, 3-phenyl-2-propenyl ester, Cinnamyl alcohol, butyrate, 3-Phenyl-2-propen-1-yl butyrate, Cinnamyl n-butyrate, Cinnamyl butanoate, NSC 30528, 3-Phenylprop-2-enyl butanoate, cinnamyl butanoate, butyric acid, cinnamyl ester, 3-phenyl-2-propen-1-yl butanoate.

Can Cinnamyl butyrate be labeled natural?

Cinnamyl butyrate occurs in nature, so the label depends on the route: cinnamyl butyrate won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized cinnamyl butyrate is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Cinnamyl butyrate is FEMA GRAS under FEMA number 2296. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 09.053, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 652, evaluated at the 55th meeting in 2000. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Cinnamyl butyrate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 103-61-7, where EPA names it Butanoic acid, 3-phenyl-2-propen-1-yl ester.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, fruity, floral, buttery, tropical.

Where it is used

Cinnamyl butyrate is used in beverage, confection, fruit flavors, bakery and ice cream, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Cinnamyl butyrate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Propyl cinnamate293887%In nature
Cinnamyl isobutyrate229785%In nature
cis-3-Hexenyl benzoate368885%In nature
3-Hexenyl phenylacetate363383%In nature
Isopropyl cinnamate293982%In nature

More esters in this index

3-Oxotetradecanoic acid glyceride · Isoamyl cinnamate · Propyleneglycol mono-2-methylbutyrate · Menthyl propionate · Decyl propionate · cis-3-Hexenyl valerate

Cinnamyl butyrate FAQ

Does cinnamyl butyrate have FEMA GRAS status?

Cinnamyl butyrate holds FEMA GRAS status under FEMA number 2296. It is also codified at 21 CFR 172.515.

How do I cite cinnamyl butyrate by FEMA or CAS number?

Cite cinnamyl butyrate as FEMA 2296 or CAS 103-61-7; both point to the same entry. FEMA files it in the fruity flavor category.

Can cinnamyl butyrate be labeled a natural flavor?

Since cinnamyl butyrate is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when cinnamyl butyrate is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

Can cinnamyl butyrate be used in the EU and UK?

Cinnamyl butyrate is on the EU Union List of flavouring substances as FL 09.053 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated cinnamyl butyrate?

Yes. JECFA number 652, evaluated at the 55th meeting in 2000. Conclusion: no safety concern at current levels of intake.

What does cinnamyl butyrate smell and taste like, and where is it used?

The odor of cinnamyl butyrate is sweet, fruity, floral, buttery, tropical. Typical uses are beverage, confection, fruit flavors, bakery and ice cream.

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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as CINNAMYL BUTYRATE under CAS 103-61-7 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.