Flavor ingredient regulatory record

Dihydrocarvyl acetate

Dihydrocarvyl acetate is an ester in the fruity family, FEMA GRAS under FEMA number 2380 (CAS 20777-49-5). Its odor is sweet, fruity, herbal, floral, citrus.

FEMA
2380
CAS
20777-49-5
JECFA
379
EU FL
09.216
Formula
C12H20O2
EC
244-029-9

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 20777-49-5.

Structure

2D structure of Dihydrocarvyl acetate
Structure of Dihydrocarvyl acetate, C12H20O2. Drawn from the canonical SMILES.

Identity

IUPAC name (2-methyl-5-prop-1-en-2-ylcyclohexyl) acetate
CAS number 20777-49-5
FEMA number 2380
Molecular formula C12H20O2
Molecular weight 196.29 g/mol
SMILES C=C(C)C1CCC(C)C(OC(C)=O)C1
InChIKey TUSIZTVSUSBSQI-UHFFFAOYSA-N
PubChem CID 30248
EC number 244-029-9
FDA UNII XC721O44HW
EPA DTXSID DTXSID501031358
Chemical class Ester
Boiling point 234 °C
Flash point 103 °C

Also known as: Cyclohexanol, 2-methyl-5-(1-methylethenyl)-, 1-acetate, (1R,2R,5R)-rel-, p-Menth-8-en-2-ol, acetate, Cyclohexanol, 2-methyl-5-(1-methylethenyl)-, acetate, (1α,2β,5α)-, Cyclohexanol, 2-methyl-5-(1-methylethenyl)-, acetate, (1R,2R,5R)-rel-, Dihydrocarveol acetate, Dihydrocarveyl acetate., trans-Dihydrocarvyl acetate, (±)-Dihydrocarvyl acetate, tuberyl acetate, dihydrocarveyl acetate, carhydrine, 8-p-menthen-2-yl acetate.

Can Dihydrocarvyl acetate be labeled natural?

Dihydrocarvyl acetate occurs in nature, so the label depends on the route: dihydrocarvyl acetate won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized dihydrocarvyl acetate is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Dihydrocarvyl acetate is FEMA GRAS under FEMA number 2380. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 09.216, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (JECFA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 379, evaluated at the 51st meeting in 1998. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Dihydrocarvyl acetate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 20777-49-5, where EPA names it Cyclohexanol, 2-methyl-5-(1-methylethenyl)-, 1-acetate, (1R,2R,5R)-rel-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, fruity, herbal, floral, citrus.

Where it is used

Dihydrocarvyl acetate is used in beverage, confection, fruit flavors, perfume and cosmetics, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Dihydrocarvyl acetate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
cis and trans-p-1(7)8-Menthadien-2-yl acetate384893%Not determined
Carvyl propionate225187%In nature
p-Mentha-1,8-dien-7-yl acetate356179%In nature
1-p-Menthen-9-yl acetate356672%In nature
Dihydronootkatone377669%In nature

More esters in this index

Ethyl alpha-acetylcinnamate · Methyl thiobutyrate · Phenethyl isovalerate · Citric acid ester of mono-and di-glycerides of fatty acids · Benzyl 2-methoxyethyl acetal · Ethyl Caprylate

Dihydrocarvyl acetate FAQ

Does dihydrocarvyl acetate have FEMA GRAS status?

Dihydrocarvyl acetate holds FEMA GRAS status under FEMA number 2380. It is also codified at 21 CFR 172.515.

How do I cite dihydrocarvyl acetate by FEMA or CAS number?

Cite dihydrocarvyl acetate as FEMA 2380 or CAS 20777-49-5; both point to the same entry. FEMA files it in the fruity flavor category.

Can dihydrocarvyl acetate be labeled a natural flavor?

Since dihydrocarvyl acetate is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when dihydrocarvyl acetate is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

Can dihydrocarvyl acetate be used in the EU and UK?

Dihydrocarvyl acetate is on the EU Union List of flavouring substances as FL 09.216 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated dihydrocarvyl acetate?

Yes. JECFA number 379, evaluated at the 51st meeting in 1998. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

What does dihydrocarvyl acetate smell and taste like, and where is it used?

The odor of dihydrocarvyl acetate is sweet, fruity, herbal, floral, citrus. Typical uses are beverage, confection, fruit flavors, perfume and cosmetics.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as DIHYDROCARVYL ACETATE under CAS 20777-49-5 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.