Flavor ingredient regulatory record
(E,E)-2,4-Octadien-1-ol
(E,E)-2,4-Octadien-1-ol is an alcohol in the fruity family, FEMA GRAS under FEMA number 3956 (CAS 18409-20-6). Its odor is sweet, fruity, floral, herbaceous, green.
- FEMA
- 3956
- CAS
- 18409-20-6
- JECFA
- 1180
- Formula
- C8H14O
GRAS status: FEMA GRAS, publication 19. Recorded by FDA in the Substances Added to Food inventory under CAS 18409-20-6.
Structure
Identity
Also known as: 2,4-Octadien-1-ol, (2E,4E)-, 2,4-Octadien-1-ol, (E,E)-, (2E,4E)-2,4-Octadien-1-ol, trans-2,4-Octadienol, 2,4-octadien-1-ol, (2e,4e)-, 2,4-octadien-1-ol, (2e,4e)-2,4-octadien-1-ol, 2,4-octadien-1-ol, (e,e)-, 2,4-octadien-1-ol, trans,trans-, (e,e)-2,4-octadien-1-ol [fhfi], (2e,4e)-octa-2,4-dien-1-ol, (2z,4z)-octa-2,4-dien-1-ol.
Can (E,E)-2,4-Octadien-1-ol be labeled natural?
(E,E)-2,4-Octadien-1-ol occurs in nature, so the label depends on the route: (E,E)-2,4-Octadien-1-ol won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized (E,E)-2,4-Octadien-1-ol is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic (E,E)-2,4-Octadien-1-ol identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
(E,E)-2,4-Octadien-1-ol is FEMA GRAS under FEMA number 3956. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for (E,E)-2,4-Octadien-1-ol. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
JECFA number 1180, evaluated at the 61st meeting in 2003. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. (E,E)-2,4-Octadien-1-ol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 18409-20-6, where EPA names it 2,4-Octadien-1-ol, (2E,4E)-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, floral, herbaceous, green.
Where it is used
(E,E)-2,4-Octadien-1-ol is used in beverage, confection, fruit flavors and flavoring agents, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to (E,E)-2,4-Octadien-1-ol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2,4-Nonadien-1-ol | 3951 | 98% | In nature |
| cis-3-Octen-1-ol | 3467 | 97% | In nature |
| 2-Octen-1-ol | 3887 | 97% | In nature |
| cis-2-Octenol | 4615 | 97% | In nature |
| cis-5-Octen-1-ol | 3722 | 96% | In nature |
More alcohols in this index
1-Phenyl-3-methyl-3-pentanol · Hexan-3-ol · (Z,Z)-3,6-Nonadien-1-ol · Tetrahydrofurfuryl alcohol · 5-Methylfurfuryl alcohol · alpha-Amylcinnamyl alcohol
(E,E)-2,4-Octadien-1-ol FAQ
Is (E,E)-2,4-Octadien-1-ol on the FEMA GRAS list?
It is. FEMA number 3956 covers (E,E)-2,4-Octadien-1-ol. It is also codified at 21 CFR 172.515.
What is the FEMA number for (E,E)-2,4-Octadien-1-ol?
The FEMA number for (E,E)-2,4-Octadien-1-ol is 3956 and its CAS registry number is 18409-20-6. FEMA files it in the fruity flavor category.
Is (E,E)-2,4-Octadien-1-ol natural or artificial?
Since (E,E)-2,4-Octadien-1-ol is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when (E,E)-2,4-Octadien-1-ol is synthesized. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic (E,E)-2,4-Octadien-1-ol identical-to-natural.
Is (E,E)-2,4-Octadien-1-ol approved in the EU?
No EU FL number is on file for (E,E)-2,4-Octadien-1-ol. It has a JECFA evaluation (JECFA 1180), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.
Has JECFA evaluated (E,E)-2,4-Octadien-1-ol?
Yes. JECFA number 1180, evaluated at the 61st meeting in 2003. Conclusion: no safety concern at current levels of intake.
What is (E,E)-2,4-Octadien-1-ol used for?
(E,E)-2,4-Octadien-1-ol is described as sweet, fruity, floral, herbaceous, green. It shows up in beverage, confection, fruit flavors and flavoring agents.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (E,E)-2,4-OCTADIEN-1-OL under CAS 18409-20-6 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.