Flavor ingredient regulatory record

alpha,alpha-Dimethylphenethyl alcohol

alpha,alpha-Dimethylphenethyl alcohol is an alcohol in the fruity family, FEMA GRAS under FEMA number 2393 (CAS 100-86-7). Its odor is sweet, floral, fruity, rosy, slightly spicy.

FEMA
2393
CAS
100-86-7
JECFA
1653
EU FL
02.035
Formula
C10H14O
EC
202-896-0

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 100-86-7.

Structure

2D structure of alpha,alpha-Dimethylphenethyl alcohol
Structure of alpha,alpha-Dimethylphenethyl alcohol, C10H14O. Drawn from the canonical SMILES.

Identity

IUPAC name 2-methyl-1-phenylpropan-2-ol
CAS number 100-86-7
FEMA number 2393
Molecular formula C10H14O
Molecular weight 150.22 g/mol
SMILES CC(C)(O)Cc1ccccc1
InChIKey RIWRBSMFKVOJMN-UHFFFAOYSA-N
PubChem CID 7531
EC number 202-896-0
FDA UNII N95NCI59MI
EPA DTXSID DTXSID1047601
Chemical class Alcohol
Boiling point 214 °C
Flash point 7 °C

Also known as: Benzeneethanol, α,α-dimethyl-, Phenethyl alcohol, α,α-dimethyl-, α,α-Dimethylbenzeneethanol, Dimethylbenzylcarbinol, α,α-Dimethylphenethyl alcohol, 1,1-Dimethyl-2-phenylethanol, DMBC, Benzyldimethylcarbinol, 1,1-Dimethylphenylethanol, α,α-Dimethylphenethanol, 2-Hydroxy-2-methyl-1-phenylpropane, 2-Methyl-1-phenyl-2-propanol.

Can alpha,alpha-Dimethylphenethyl alcohol be labeled natural?

Nature makes alpha,alpha-Dimethylphenethyl alcohol, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial alpha,alpha-Dimethylphenethyl alcohol, same molecule. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

alpha,alpha-Dimethylphenethyl alcohol is FEMA GRAS under FEMA number 2393. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 02.035, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1653, evaluated at the 68th meeting in 2007. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list. Listed on the EPA TSCA inventory.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. alpha,alpha-Dimethylphenethyl alcohol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 100-86-7, where EPA names it Benzeneethanol, .alpha.,.alpha.-dimethyl-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, floral, fruity, rosy, slightly spicy.

Where it is used

alpha,alpha-Dimethylphenethyl alcohol is used in beverage, confection, fragrance, flavoring and personal care, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to alpha,alpha-Dimethylphenethyl alcohol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
2-Isobutylpyridine337077%In nature
2-Methyl-4-phenyl-2-butanol362973%In nature
p-alpha,alpha-Trimethylbenzyl alcohol324266%In nature
3-Isobutylpyridine337163%In nature
4-Phenyl-2-butanol287958%In nature

More alcohols in this index

3-Phenyl-1-propanol · 3-Decanol · cis-3-Octen-1-ol · Furfuryl alcohol · Nonyl alcohol · cis-3-Nonen-1-ol

alpha,alpha-Dimethylphenethyl alcohol FAQ

Is alpha,alpha-Dimethylphenethyl alcohol on the FEMA GRAS list?

It is. FEMA number 2393 covers alpha,alpha-Dimethylphenethyl alcohol. The Code of Federal Regulations lists it at 21 CFR 172.515.

What is the FEMA number for alpha,alpha-Dimethylphenethyl alcohol?

The FEMA number for alpha,alpha-Dimethylphenethyl alcohol is 2393 and its CAS registry number is 100-86-7. Its flavor category is fruity.

What is alpha,alpha-Dimethylphenethyl alcohol used for?

alpha,alpha-Dimethylphenethyl alcohol is described as sweet, floral, fruity, rosy, slightly spicy. It shows up in beverage, confection, fragrance, flavoring and personal care.

What did JECFA conclude about alpha,alpha-Dimethylphenethyl alcohol?

JECFA evaluated alpha,alpha-Dimethylphenethyl alcohol at the 68th meeting in 2007 under JECFA number 1653. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Is alpha,alpha-Dimethylphenethyl alcohol approved in the EU?

Yes. FL 02.035 is the Union List entry for alpha,alpha-Dimethylphenethyl alcohol, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Is alpha,alpha-Dimethylphenethyl alcohol natural or artificial?

The process decides for alpha,alpha-Dimethylphenethyl alcohol. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic alpha,alpha-Dimethylphenethyl alcohol is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ALPHA,ALPHA-DIMETHYLPHENETHYL ALCOHOL under CAS 100-86-7 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.