Flavor ingredient regulatory record

Ethyl trans-2-cis-4-decadienoate

Ethyl trans-2-cis-4-decadienoate is an ester in the fruity family, FEMA GRAS under FEMA number 3148 (CAS 3025-30-7). Its odor is sweet, fruity, tropical, floral, berry.

FEMA
3148
CAS
3025-30-7
JECFA
1192
EU FL
09.260
Formula
C12H20O2
EC
221-178-8

GRAS status: FEMA GRAS, publication 4. Recorded by FDA in the Substances Added to Food inventory under CAS 3025-30-7.

Structure

2D structure of Ethyl trans-2-cis-4-decadienoate
Structure of Ethyl trans-2-cis-4-decadienoate, C12H20O2. Drawn from the canonical SMILES.

Identity

IUPAC name ethyl (2E,4Z)-deca-2,4-dienoate
CAS number 3025-30-7
FEMA number 3148
Molecular formula C12H20O2
Molecular weight 196.29 g/mol
SMILES CCCCC/C=C\C=C\C(=O)OCC
InChIKey OPCRGEVPIBLWAY-QNRZBPGKSA-N
PubChem CID 5281162
EC number 221-178-8
FDA UNII 79P6KS9Y5Z
EPA DTXSID DTXSID0041357
Chemical class Ester
Boiling point 72 °C
Flash point 19 °C

Also known as: 2,4-Decadienoic acid, ethyl ester, (2E,4Z)-, 2,4-Decadienoic acid, ethyl ester, (E,Z)-, Ethyl trans-2,cis-4-decadienoate, Ethyl (2E,4Z)-decadienoate, Ethyl (E,Z)-2,4-decadienoate, Ethyl (2E,4Z)-2,4-decadienoate, Pear ester, ethyl (2e,4z)-deca-2,4-dienoate, ethyl (2e,4z)-decadienoate, ethyl (e,z)-2,4-decadienoate, 2,4-decadienoic acid, ethyl ester, (2e,4z)-, ethyl trans-2,cis-4-decadienoate.

Can Ethyl trans-2-cis-4-decadienoate be labeled natural?

Ethyl trans-2-cis-4-decadienoate occurs in nature, so the label depends on the route: ethyl trans-2-cis-4-decadienoate won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized ethyl trans-2-cis-4-decadienoate is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Ethyl trans-2-cis-4-decadienoate is FEMA GRAS under FEMA number 3148. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 09.260, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1192, evaluated at the 61st meeting in 2003. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Ethyl trans-2-cis-4-decadienoate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 3025-30-7, where EPA names it 2,4-Decadienoic acid, ethyl ester, (2E,4Z)-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, fruity, tropical, floral, berry.

Where it is used

Ethyl trans-2-cis-4-decadienoate is used in beverage, confection, fruit flavors, bakery and desserts, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Ethyl trans-2-cis-4-decadienoate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Propyl 2,4-decadienoate364896%In nature
Methyl (E)-2-(Z)-4-decadienoate385995%In nature
trans-2-Octen-1-yl butanoate351790%In nature

More esters in this index

3-Hexenyl 3-methylbutanoate · Furfuryl pentanoate · alpha-Methylbenzyl acetate · Isoamyl salicylate · l-Menthyl acetoacetate · Ethyl hexadecanoate

Ethyl trans-2-cis-4-decadienoate FAQ

Does ethyl trans-2-cis-4-decadienoate have FEMA GRAS status?

Ethyl trans-2-cis-4-decadienoate holds FEMA GRAS status under FEMA number 3148. It is also codified at 21 CFR 172.515.

How do I cite ethyl trans-2-cis-4-decadienoate by FEMA or CAS number?

Cite ethyl trans-2-cis-4-decadienoate as FEMA 3148 or CAS 3025-30-7; both point to the same entry. FEMA files it in the fruity flavor category.

Can ethyl trans-2-cis-4-decadienoate be labeled a natural flavor?

Since ethyl trans-2-cis-4-decadienoate is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when ethyl trans-2-cis-4-decadienoate is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

Can ethyl trans-2-cis-4-decadienoate be used in the EU and UK?

Ethyl trans-2-cis-4-decadienoate is on the EU Union List of flavouring substances as FL 09.260 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated ethyl trans-2-cis-4-decadienoate?

Yes. JECFA number 1192, evaluated at the 61st meeting in 2003. Conclusion: no safety concern at current levels of intake.

What does ethyl trans-2-cis-4-decadienoate smell and taste like, and where is it used?

The odor of ethyl trans-2-cis-4-decadienoate is sweet, fruity, tropical, floral, berry. Typical uses are beverage, confection, fruit flavors, bakery and desserts.

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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ETHYL TRANS-2,CIS-4-DECADIENOATE under CAS 3025-30-7 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.