Flavor ingredient regulatory record

Cinnamyl formate

Cinnamyl formate is an ester in the fruity family, FEMA GRAS under FEMA number 2299 (CAS 104-65-4). Its odor is sweet, fruity, floral, cinnamon, estery.

FEMA
2299
CAS
104-65-4
JECFA
649
EU FL
09.085
Formula
C10H10O2
EC
203-223-3

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 104-65-4.

Structure

2D structure of Cinnamyl formate
Structure of Cinnamyl formate, C10H10O2. Drawn from the canonical SMILES.

Identity

IUPAC name [(E)-3-phenylprop-2-enyl] formate
CAS number 104-65-4
FEMA number 2299
Molecular formula C10H10O2
Molecular weight 162.19 g/mol
SMILES O=COC/C=C/c1ccccc1
InChIKey LBHJXKYRYCUGPD-QPJJXVBHSA-N
PubChem CID 5354883
EC number 203-223-3
FDA UNII 896AGS89RD
EPA DTXSID DTXSID00861714
Chemical class Ester
Boiling point 138 °C
Flash point 53 °C

Also known as: 2-Propen-1-ol, 3-phenyl-, 1-formate, Cinnamyl alcohol, formate, 2-Propen-1-ol, 3-phenyl-, formate, Cinnamyl methanoate, γ-Phenylallyl formate, 3-Phenyl-2-propen-1-yl formate, NSC 21737, 3-Phenyl-2-propen-1-ol formate, cinnamyl alcohol, formate, 2-propen-1-ol, 3-phenyl-, formate, 2-propen-1-ol, 3-phenyl-, 1-formate, cinnamyl methanoate.

Can Cinnamyl formate be labeled natural?

The process decides for cinnamyl formate. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic cinnamyl formate is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Cinnamyl formate is FEMA GRAS under FEMA number 2299. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 09.085, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 649, evaluated at the 55th meeting in 2000. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Cinnamyl formate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 104-65-4, where EPA names it 2-Propen-1-ol, 3-phenyl-, 1-formate.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, fruity, floral, cinnamon, estery.

Where it is used

Cinnamyl formate is used in beverage, confection, baked goods, flavoring and desserts, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Cinnamyl formate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Methyl cinnamate269885%In nature
Cinnamyl alcohol229483%In nature
Phenethyl formate286478%In nature
Ethyl cinnamate243078%In nature
Cinnamaldehyde228678%In nature

More esters in this index

Methyl anthranilate · Methyl thiobutyrate · Methyl 2-nonynoate · Propyleneglycol monobutyrate · Methyl myristate · Myrtenyl acetate

Cinnamyl formate FAQ

Does cinnamyl formate have FEMA GRAS status?

Cinnamyl formate holds FEMA GRAS status under FEMA number 2299. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite cinnamyl formate by FEMA or CAS number?

Cite cinnamyl formate as FEMA 2299 or CAS 104-65-4; both point to the same entry. Its flavor category is fruity.

What does cinnamyl formate smell and taste like, and where is it used?

The odor of cinnamyl formate is sweet, fruity, floral, cinnamon, estery. Typical uses are beverage, confection, baked goods, flavoring and desserts.

What did JECFA conclude about cinnamyl formate?

JECFA evaluated cinnamyl formate at the 55th meeting in 2000 under JECFA number 649. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Can cinnamyl formate be used in the EU and UK?

Yes. FL 09.085 is the Union List entry for cinnamyl formate, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Can cinnamyl formate be labeled a natural flavor?

Nature makes cinnamyl formate, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial cinnamyl formate, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic cinnamyl formate identical-to-natural.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as CINNAMYL FORMATE under CAS 104-65-4 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.