Flavor ingredient regulatory record

Isoamyl 3-(2-furan)propionate

Isoamyl 3-(2-furan)propionate is an ester in the fruity family, FEMA GRAS under FEMA number 2071 (CAS 7779-67-1). Its odor is sweet, fruity, banana, furan, estery.

FEMA
2071
CAS
7779-67-1
JECFA
1515
EU FL
13.023
Formula
C12H18O3
EC
231-932-8

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 7779-67-1.

Structure

2D structure of Isoamyl 3-(2-furan)propionate
Structure of Isoamyl 3-(2-furan)propionate, C12H18O3. Drawn from the canonical SMILES.

Identity

IUPAC name 3-methylbutyl 3-(furan-2-yl)propanoate
CAS number 7779-67-1
FEMA number 2071
Molecular formula C12H18O3
Molecular weight 210.27 g/mol
SMILES CC(C)CCOC(=O)CCc1ccco1
InChIKey ZVMWAVZRUZDYMV-UHFFFAOYSA-N
PubChem CID 538506
EC number 231-932-8
FDA UNII 4B479FVZ19
EPA DTXSID DTXSID20228406
Chemical class Ester
Boiling point 258 °C
Flash point 115 °C

Also known as: 2-Furanpropanoic acid, 3-methylbutyl ester, 2-Furanpropionic acid, isopentyl ester, Isopentyl alcohol, 2-furanpropionate, Isoamyl 2-furanpropionate, α-Isoamyl furfurylacetate, Isoamyl furylpropanoate, 3-Methylbutyl 3-(furan-2-yl)propanoate, 2-furanpropanoic acid, 3-methylbutyl ester, isoamyl 2-furanpropionate, isoamyl furylpropanoate, 3-methylbutyl furan-2-propionate, isoamyl 2-furylpropionate.

Can Isoamyl 3-(2-furan)propionate be labeled natural?

The process decides for isoamyl 3-(2-furan)propionate. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic isoamyl 3-(2-furan)propionate is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Isoamyl 3-(2-furan)propionate is FEMA GRAS under FEMA number 2071. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 13.023, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1515, evaluated at the 86th meeting in 2018. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, banana, furan, estery.

Where it is used

Isoamyl 3-(2-furan)propionate is used in beverage, confection, fruit flavors, bakery and desserts, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Isoamyl 3-(2-furan)propionate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Furfuryl octanoate339681%In nature
Isoamyl 4-(2-furan)butyrate207080%In nature
Furfuryl pentanoate339779%In nature
Isobutyl 3-(2-furan)propionate219878%In nature
Isoamyl phenylacetate208164%In nature

More esters in this index

Ethyl decanoate · Lactylated fatty acid esters of glycerol and propylene glycol · Allyl tiglate · Phenethyl cinnamate · Sodium 2-(4-methoxyphenoxy)propanoate · Propyl phenylacetate

Isoamyl 3-(2-furan)propionate FAQ

Does isoamyl 3-(2-furan)propionate have FEMA GRAS status?

Isoamyl 3-(2-furan)propionate holds FEMA GRAS status under FEMA number 2071. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite isoamyl 3-(2-furan)propionate by FEMA or CAS number?

Cite isoamyl 3-(2-furan)propionate as FEMA 2071 or CAS 7779-67-1; both point to the same entry. Its flavor category is fruity.

What does isoamyl 3-(2-furan)propionate smell and taste like, and where is it used?

The odor of isoamyl 3-(2-furan)propionate is sweet, fruity, banana, furan, estery. Typical uses are beverage, confection, fruit flavors, bakery and desserts.

What did JECFA conclude about isoamyl 3-(2-furan)propionate?

JECFA evaluated isoamyl 3-(2-furan)propionate at the 86th meeting in 2018 under JECFA number 1515. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Can isoamyl 3-(2-furan)propionate be used in the EU and UK?

Yes. FL 13.023 is the Union List entry for isoamyl 3-(2-furan)propionate, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Can isoamyl 3-(2-furan)propionate be labeled a natural flavor?

Nature makes isoamyl 3-(2-furan)propionate, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial isoamyl 3-(2-furan)propionate, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic isoamyl 3-(2-furan)propionate identical-to-natural.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ISOAMYL 3-(2-FURAN)PROPIONATE under CAS 7779-67-1 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.