Flavor ingredient regulatory record
Isoamyl 4-(2-furan)butyrate
Isoamyl 4-(2-furan)butyrate is an ester in the fruity family, FEMA GRAS under FEMA number 2070 (CAS 7779-66-0). Its odor is sweet, fruity, banana, furan, estery.
- FEMA
- 2070
- CAS
- 7779-66-0
- JECFA
- 1516
- EU FL
- 13.021
- Formula
- C13H20O3
GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 7779-66-0.
Structure
Identity
Also known as: 2-Furanbutanoic acid, 3-methylbutyl ester, 2-Furanbutyric acid, isopentyl ester, Isopentyl alcohol, 2-furanbutyrate, 3-Methylbutyl 2-furanbutanoate, Isoamyl 2-furanbutyrate, 3-Methylbutyl 4-(furan-2-yl)butanoate, 2-furanbutanoic acid, 3-methylbutyl ester, isoamyl 2-furanbutyrate, 3-methylbutyl 2-furanbutanoate, 3-methylbutyl 2-furanbutyrate, isopentyl 2-furanbutyrate, isoamyl 4-(2-furyl)butyrate.
Can Isoamyl 4-(2-furan)butyrate be labeled natural?
Since isoamyl 4-(2-furan)butyrate is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when isoamyl 4-(2-furan)butyrate is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
Isoamyl 4-(2-furan)butyrate is FEMA GRAS under FEMA number 2070. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 13.021, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1516, evaluated at the 65th meeting in 2006. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Sweet, fruity, banana, furan, estery.
Where it is used
Isoamyl 4-(2-furan)butyrate is used in beverage, confection, fruit flavors, bakery and ice cream, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Isoamyl 4-(2-furan)butyrate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Isoamyl 3-(2-furan)propionate | 2071 | 80% | In nature |
| Furfuryl octanoate | 3396 | 70% | In nature |
| Phenethyl isovalerate | 2871 | 67% | In nature |
| Isobutyl 3-(2-furan)propionate | 2198 | 51% | In nature |
| Isoamyl phenylacetate | 2081 | 50% | In nature |
More esters in this index
Isobutyl acetate · cis-3-Hexenyl anthranilate · Ethyl undecanoate · Ethyl anthranilate · Ethyl 4-pentenoate · Methyl anthranilate
Isoamyl 4-(2-furan)butyrate FAQ
Is isoamyl 4-(2-furan)butyrate FEMA GRAS?
Yes. The FEMA Expert Panel lists isoamyl 4-(2-furan)butyrate as GRAS under FEMA number 2070. It is also codified at 21 CFR 172.515.
What are the FEMA and CAS numbers for isoamyl 4-(2-furan)butyrate?
Isoamyl 4-(2-furan)butyrate is FEMA 2070, CAS 7779-66-0. FEMA files it in the fruity flavor category.
Does isoamyl 4-(2-furan)butyrate count as natural in the US and the EU?
Isoamyl 4-(2-furan)butyrate occurs in nature, so the label depends on the route: isoamyl 4-(2-furan)butyrate won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized isoamyl 4-(2-furan)butyrate is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic isoamyl 4-(2-furan)butyrate identical-to-natural.
Is isoamyl 4-(2-furan)butyrate on the EU Union List?
Isoamyl 4-(2-furan)butyrate is on the EU Union List of flavouring substances as FL 13.021 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated isoamyl 4-(2-furan)butyrate?
Yes. JECFA number 1516, evaluated at the 65th meeting in 2006. Conclusion: no safety concern at current levels of intake.
How is isoamyl 4-(2-furan)butyrate described, and where does it show up?
Flavorists describe isoamyl 4-(2-furan)butyrate as sweet, fruity, banana, furan, estery. It is used in beverage, confection, fruit flavors, bakery and ice cream.
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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ISOAMYL 4-(2-FURAN)BUTYRATE under CAS 7779-66-0 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.