Flavor ingredient regulatory record

Tetramethyl ethylcyclohexenone

Tetramethyl ethylcyclohexenone is a natural complex flavoring material in the fruity family, FEMA GRAS under FEMA number 3061 (CAS 17369-60-7). Its odor is sweet, fruity, floral, green, tropical.

FEMA
3061
CAS
17369-60-7
JECFA
1111
EU FL
07.035

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 977045-69-4.

Structure

Material

Tetramethyl ethylcyclohexenone is a natural complex material rather than a single molecule, so it has no one structure. FEMA lists it as Tetramethyl ethylcyclohexenone (mixture of isomers).

Identity

CAS number 17369-60-7
FEMA number 3061
Molecular weight 180.29 g/mol
FDA UNII 9MM11393HF
EPA DTXSID DTXSID90864774
Chemical class Ketone
Boiling point 113 °C
Flash point 90 °C

Also known as: 2-Cyclohexen-1-one, 5-ethyl-2,3,4,5-tetramethyl-, 5-Ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one, 5-ethyl-2,3,4,5-tetramethylcyclohexen-1-one, 5-ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one, 5-ethyl-2,3,4,5-tetramethyl-2-cyclohexenone, 2-cyclohexen-1-one, 5-ethyl-2,3,4,5-tetramethyl-, (+-)-5-ethyl-2,3,4,5-tetramethyl-2-cyclohexenone, 5-ethyl-2,3,4,5-tetramethyl-2-cyclohexenone, (+-)-, 5-ethyl-2,3,4,5-tetramethylcyclohex-2-en-1-one, 5-ethyl-2,3,4,5-tetramethyl-2-cyclohexenone, (+/-)-.

Can Tetramethyl ethylcyclohexenone be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

Tetramethyl ethylcyclohexenone is FEMA GRAS under FEMA number 3061. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 07.035, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1111, evaluated at the 73rd meeting in 2011. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, floral, green, tropical.

Where it is used

Tetramethyl ethylcyclohexenone is used in beverage, confection, fruit flavors and flavoring agents, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Tetramethyl ethylcyclohexenone by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Nootkatone316672%In nature
alpha-Irone259770%In nature
Dehydronootkatone409168%In nature
2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol452166%In nature
beta-Isomethylionone415166%In nature

More ketones in this index

4-Heptanone · Mixture of 3-Hydroxy-5-methyl-2-hexanone and 2-Hydroxy-5-methyl-3-hexanone · Epoxy oxophorone · (E)-1,5-Octadien-3-one · 5-Methyl-3-hexen-2-one · 9-Decen-2-one

Tetramethyl ethylcyclohexenone FAQ

Does tetramethyl ethylcyclohexenone have FEMA GRAS status?

Tetramethyl ethylcyclohexenone holds FEMA GRAS status under FEMA number 3061. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite tetramethyl ethylcyclohexenone by FEMA or CAS number?

Cite tetramethyl ethylcyclohexenone as FEMA 3061 or CAS 17369-60-7; both point to the same entry. Its flavor category is fruity.

What does tetramethyl ethylcyclohexenone smell and taste like, and where is it used?

The odor of tetramethyl ethylcyclohexenone is sweet, fruity, floral, green, tropical. Typical uses are beverage, confection, fruit flavors and flavoring agents.

What did JECFA conclude about tetramethyl ethylcyclohexenone?

JECFA evaluated tetramethyl ethylcyclohexenone at the 73rd meeting in 2011 under JECFA number 1111. The panel concluded: no safety concern at current levels of intake.

Can tetramethyl ethylcyclohexenone be used in the EU and UK?

Yes. FL 07.035 is the Union List entry for tetramethyl ethylcyclohexenone, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as TETRAMETHYL ETHYLCYCLOHEXENONE (MIXTURE OF ISOMERS) under CAS 977045-69-4 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.