Flavor ingredient regulatory record
2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol
2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol is a terpene in the fruity family, FEMA GRAS under FEMA number 4521 (CAS 97866-86-9). Its odor is sweet, fruity, floral, herbaceous, citrus.
- FEMA
- 4521
- CAS
- 97866-86-9
- JECFA
- 2198
GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 97866-86-9.
Structure
Under review
The structure for 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol is still under identity review, so no drawing is shown until the record is confirmed.
Identity
Also known as: 1,4,4,7a-tetramethyl-2,4,5,7a-tetrahydro-1h-inden-2-ol, 1,4,4,7a-tetramethyl-2,5-dihydro-1h-inden-2-ol, 2,4,5,7a-tetrahydro-1,4,4,7a-tetramethyl-1h-inden-2-ol, 2,2,6,7-tetramethyl bicyclo(4.3.0)nona-4,9(1)-dien-8-ol, 2,4,5,7alpha-tetrahydro-1,4,4,7a-tetramethyl-1h-inden-2-ol, 2,2,6,7-tetramethyl bicyclo(4,3,0)nona-4,9(1)-dien-8-ol, 2,2,6,7-tetramethylbicyclo[4.3.0]nona-1(9),4-dien-8-ol.
Can 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol be labeled natural?
Nature makes 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol is FEMA GRAS under FEMA number 4521. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
JECFA number 2198, evaluated at the 63rd meeting in 2004. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Sweet, fruity, floral, herbaceous, citrus.
Where it is used
2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol is used in beverage, confection, fruit flavors, aromatic compounds and perfumes, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2,3,3-Trimethylindan-1-one | 4556 | 74% | Not determined |
| Tetramethyl ethylcyclohexenone | 3061 | 73% | Not determined |
| (+/-)-(2,6,6,-Trimethyl-2-hydroxycyclohexylidene)acetic acid gamma-lactone | 4020 | 72% | In nature |
| Fenchyl alcohol | 2480 | 71% | In nature |
| (+)-Cedrol | 4503 | 70% | In nature |
More terpenes in this index
Myrtenol · beta-Farnesene · (E,R)-3,7-Dimethyl-1,5,7-octatrien-3-ol · Farnesene · d-8-p-Menthene-1,2-epoxide · 2,2,6-Trimethyl-6-vinyltetrahydropyran
2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol FAQ
Is 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol FEMA GRAS?
Yes. The FEMA Expert Panel lists 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol as GRAS under FEMA number 4521. The Code of Federal Regulations lists it at 21 CFR 172.515.
What are the FEMA and CAS numbers for 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol?
2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol is FEMA 4521, CAS 97866-86-9. Its flavor category is fruity.
How is 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol described, and where does it show up?
Flavorists describe 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol as sweet, fruity, floral, herbaceous, citrus. It is used in beverage, confection, fruit flavors, aromatic compounds and perfumes.
What did JECFA conclude about 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol?
JECFA evaluated 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol at the 63rd meeting in 2004 under JECFA number 2198. The panel concluded: no safety concern at current levels of intake.
Is 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol approved in the EU?
No EU FL number is on file for 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol. It has a JECFA evaluation (JECFA 2198), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.
Does 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol count as natural in the US and the EU?
The process decides for 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 2,2,6,7-Tetramethylbicyclo[4.3.0]nona-4,9(1)-dien-8-ol identical-to-natural.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2,2,6,7-TETRAMETHYLBICYCLO[4.3.0]NONA-4,9(1)-DIEN-8-OL under CAS 97866-86-9 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.