Flavor ingredient regulatory record

Allyl alpha-ionone

Allyl alpha-ionone is a terpene in the fruity family, FEMA GRAS under FEMA number 2033 (CAS 79-78-7). Its odor is floral, sweet, fruity, berry, woody.

FEMA
2033
CAS
79-78-7
JECFA
401
EU FL
07.061
Formula
C16H24O
EC
201-225-9

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 79-78-7.

Structure

2D structure of Allyl alpha-ionone
Structure of Allyl alpha-ionone, C16H24O. Drawn from the canonical SMILES.

Identity

IUPAC name (1E)-1-(2,6,6-trimethylcyclohex-2-en-1-yl)hepta-1,6-dien-3-one
CAS number 79-78-7
FEMA number 2033
Molecular formula C16H24O
Molecular weight 232.37 g/mol
SMILES C=CCCC(=O)/C=C/C1C(C)=CCCC1(C)C
InChIKey FXCYGAGBPZQRJE-ZHACJKMWSA-N
PubChem CID 5365976
EC number 201-225-9
FDA UNII 8IP66F9ODG
EPA DTXSID DTXSID4047591
Chemical class Terpene
Boiling point 109 °C
Flash point 38 °C

Also known as: 1,6-Heptadien-3-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-, 1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-1,6-heptadien-3-one, Allyl-α-ionone, Cetone V, Hexalon (fragrance), Hexalon, 1-(2,6,6-Trimethylcyclohex-2-enyl)hepta-1,6-dien-3-one, allyl-alpha-ionone, ionone, allyl alpha-, 1,6-heptadien-3-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-, cetone v, allyl ionone.

Can Allyl alpha-ionone be labeled natural?

Nature makes allyl alpha-ionone, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial allyl alpha-ionone, same molecule. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Allyl alpha-ionone is FEMA GRAS under FEMA number 2033. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 07.061, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (JECFA/EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 401, evaluated at the 51st meeting in 1998. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Allyl alpha-ionone appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 79-78-7, where EPA names it 1,6-Heptadien-3-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Floral, sweet, fruity, berry, woody.

Where it is used

Allyl alpha-ionone is used in beverage, confection, fragrance, flavoring and cosmetics, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Allyl alpha-ionone by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Ionone317584%In nature
alpha-Irone259781%In nature
alpha-Ionone259479%In nature
Dihydro-alpha-ionone362879%In nature
Methyl-alpha-ionone271179%In nature

More terpenes in this index

3,7-Dimethyl-1,3,6-octatriene · alpha-Campholenic alcohol · alpha-Phellandrene · d-3-Carene · 10-Hydroxymethylene-2-pinene · d-8-p-Menthene-1,2-epoxide

Allyl alpha-ionone FAQ

Is allyl alpha-ionone on the FEMA GRAS list?

It is. FEMA number 2033 covers allyl alpha-ionone. The Code of Federal Regulations lists it at 21 CFR 172.515.

What is the FEMA number for allyl alpha-ionone?

The FEMA number for allyl alpha-ionone is 2033 and its CAS registry number is 79-78-7. Its flavor category is fruity.

What is allyl alpha-ionone used for?

Allyl alpha-ionone is described as floral, sweet, fruity, berry, woody. It shows up in beverage, confection, fragrance, flavoring and cosmetics.

What did JECFA conclude about allyl alpha-ionone?

JECFA evaluated allyl alpha-ionone at the 51st meeting in 1998 under JECFA number 401. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Is allyl alpha-ionone approved in the EU?

Yes. FL 07.061 is the Union List entry for allyl alpha-ionone, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Is allyl alpha-ionone natural or artificial?

The process decides for allyl alpha-ionone. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic allyl alpha-ionone is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ALLYL ALPHA-IONONE under CAS 79-78-7 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.