Flavor ingredient regulatory record
10-Hydroxymethylene-2-pinene
10-Hydroxymethylene-2-pinene is a terpene in the fruity family, FEMA GRAS under FEMA number 3938 (CAS 128-50-7). Its odor is citrusy, piney, fresh, herbal.
- FEMA
- 3938
- CAS
- 128-50-7
- JECFA
- 986
- EU FL
- 02.141
- Formula
- C11H18O
- EC
- 204-890-3
GRAS status: FEMA GRAS, publication 19. Recorded by FDA in the Substances Added to Food inventory under CAS 128-50-7.
Structure
Identity
Also known as: Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-, 2-Norpinene-2-ethanol, 6,6-dimethyl-, 6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-Dimethyl-2-norpinene-2-ethanol, Nopol (terpene), Homomyrtenol, Nopol, 10-(Hydroxymethyl)-2-pinene, NSC 1284, NSC 404962, 2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol, 2-[6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol.
Can 10-Hydroxymethylene-2-pinene be labeled natural?
Since 10-Hydroxymethylene-2-pinene is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when 10-Hydroxymethylene-2-pinene is synthesized. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
10-Hydroxymethylene-2-pinene is FEMA GRAS under FEMA number 3938. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 02.141, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 986, evaluated at the 59th meeting in 2002. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list. Listed on the EPA TSCA inventory.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. 10-Hydroxymethylene-2-pinene appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 128-50-7, where EPA names it Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Citrusy, piney, fresh, herbal.
Taste: Slightly sweet, refreshing, herbal.
Where it is used
10-Hydroxymethylene-2-pinene is used in beverage, confection, flavoring agents and aromatic products, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 10-Hydroxymethylene-2-pinene by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Verbenol | 3594 | 83% | In nature |
| Myrtenol | 3439 | 82% | In nature |
| Myrtenyl acetate | 3765 | 79% | In nature |
| Verbenone | 4216 | 76% | In nature |
| alpha-Campholenic alcohol | 3741 | 63% | In nature |
More terpenes in this index
beta-Farnesene · 4-Methylidene-2-(2-methylprop-1-enyl)oxane · d-2,8-p-Menthadien-1-ol · Carveol · Farnesene · Myrtenol
10-Hydroxymethylene-2-pinene FAQ
Is 10-Hydroxymethylene-2-pinene on the FEMA GRAS list?
It is. FEMA number 3938 covers 10-Hydroxymethylene-2-pinene. It is also codified at 21 CFR 172.515.
What is the FEMA number for 10-Hydroxymethylene-2-pinene?
The FEMA number for 10-Hydroxymethylene-2-pinene is 3938 and its CAS registry number is 128-50-7. FEMA files it in the fruity flavor category.
Is 10-Hydroxymethylene-2-pinene natural or artificial?
10-Hydroxymethylene-2-pinene occurs in nature, so the label depends on the route: 10-Hydroxymethylene-2-pinene won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized 10-Hydroxymethylene-2-pinene is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
Is 10-Hydroxymethylene-2-pinene approved in the EU?
10-Hydroxymethylene-2-pinene is on the EU Union List of flavouring substances as FL 02.141 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated 10-Hydroxymethylene-2-pinene?
Yes. JECFA number 986, evaluated at the 59th meeting in 2002. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.
What is 10-Hydroxymethylene-2-pinene used for?
10-Hydroxymethylene-2-pinene is described as citrusy, piney, fresh, herbal. On the palate it is slightly sweet, refreshing, herbal. It shows up in beverage, confection, flavoring agents and aromatic products.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 10-HYDROXYMETHYLENE-2-PINENE under CAS 128-50-7 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.