Flavor ingredient regulatory record
2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers
2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers is a natural complex flavoring material in the fruity family, FEMA GRAS under FEMA number 3971 (CAS 26486-21-5). Its odor is sweet, fruity, sulfurous, herbaceous.
- FEMA
- 3971
- CAS
- 26486-21-5
- JECFA
- 1091
- EU FL
- 13.193
GRAS status: FEMA GRAS, publication 20. Recorded by FDA in the Substances Added to Food inventory under CAS 26486-21-5.
Structure
Material
2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers is a natural complex material rather than a single molecule, so it has no one structure. FEMA lists it as 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers.
Identity
Also known as: 3-Furanthiol, tetrahydro-2,5-dimethyl-, Tetrahydro-2,5-dimethyl-3-furanthiol, 2,5-Dimethyl-3-mercaptotetrahydrofuran, 2,5-Dimethyltetrahydrofuran-3-thiol, 2,5-Dimethyloxolane-3-thiol, 2,5-dimethyltetrahydrofuran-3-thiol, 2,5-dimethyloxolane-3-thiol, 2,5-dimethyl-3-mercaptotetrahydrofuran, 2,5-dimethyl-3-tetrahydrofuranthiol, tetrahydro-2,5-dimethylfuran-3-thiol, 3-furanthiol, tetrahydro-2,5-dimethyl-, (z+e)-2,5-dimethyl-3-tetrahydrofuran thiol.
Can 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers is FEMA GRAS under FEMA number 3971. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 13.193, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1091.
Other US flags
Not on the California Proposition 65 list. Listed on the EPA TSCA inventory.
Odor and taste
Odor: Sweet, fruity, sulfurous, herbaceous.
Where it is used
2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers is used in beverage, savory dishes, snacks and seasonings, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2-Methyl-3-tetrahydrofuranthiol | 3787 | 91% | In nature |
| 2,5-Dimethyl-3-furanthiol | 3451 | 88% | In nature |
| 3-Mercapto-2-pentanone | 3300 | 86% | In nature |
| 2,4-Dimethyl-1,3-dioxolane | 4099 | 69% | Not determined |
| Cyclopentanethiol | 3262 | 69% | In nature |
More thiols in this index
2-Methyl-4-propyl-1,3-oxathiane · 2-Methyl-3-tetrahydrofuranthiol · (+/-)-2,8-Epithio-cis-p-menthane · Diisopentyl thiomalate · Allyl thiohexanoate · 1-(3-(Methylthio)-butyryl)-2,6,6-trimethylcyclohexene
2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers FAQ
Is 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers on the FEMA GRAS list?
It is. FEMA number 3971 covers 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers. The Code of Federal Regulations lists it at 21 CFR 172.515.
What is the FEMA number for 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers?
The FEMA number for 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers is 3971 and its CAS registry number is 26486-21-5. Its flavor category is fruity.
What is 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers used for?
2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers is described as sweet, fruity, sulfurous, herbaceous. It shows up in beverage, savory dishes, snacks and seasonings.
What did JECFA conclude about 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers?
JECFA evaluated 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers under JECFA number 1091.
Is 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers approved in the EU?
Yes. FL 13.193 is the Union List entry for 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2,5-DIMETHYL-3-MERCAPTOTETRAHYDROFURAN under CAS 26486-21-5 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.