Flavor ingredient regulatory record
Citronellyl anthranilate
Citronellyl anthranilate is an ester in the fruity family, FEMA GRAS under FEMA number 4086 (CAS 68555-57-7). Its odor is sweet, fruity, floral, citrus, berry.
- FEMA
- 4086
- CAS
- 68555-57-7
- JECFA
- 1539
- Formula
- C17H25NO2
GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 68555-57-7.
Structure
Identity
Also known as: 6-Octen-1-ol, 3,7-dimethyl-, 1-(2-aminobenzoate), 6-Octen-1-ol, 3,7-dimethyl-, 2-aminobenzoate, 3,7-dimethyloct-6-enyl 2-aminobenzoate, 6-octen-1-ol, 3,7-dimethyl-, 2-aminobenzoate, 3,7-dimethyloct-6-en-1-yl 2-aminobenzoate, 6-octen-1-ol, 3,7-dimethyl-, 1-(2-aminobenzoate), citronellyl anthranilate [fhfi], 3,7-dimethyl-6-octenyl 2-aminobenzoate #.
Can Citronellyl anthranilate be labeled natural?
Since citronellyl anthranilate is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when citronellyl anthranilate is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
Citronellyl anthranilate is FEMA GRAS under FEMA number 4086. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for Citronellyl anthranilate. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
JECFA number 1539, evaluated at the 65th meeting in 2005. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Citronellyl anthranilate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 68555-57-7, where EPA names it 6-Octen-1-ol, 3,7-dimethyl-, 1-(2-aminobenzoate).
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, floral, citrus, berry.
Where it is used
Citronellyl anthranilate is used in beverage, confection, fruit flavors, personal care and aromatherapy, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Citronellyl anthranilate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Linalyl anthranilate | 2637 | 79% | In nature |
| cis-3-Hexenyl anthranilate | 3925 | 74% | In nature |
More esters in this index
Dodecyl butyrate · Propyleneglycol mono-2-methylbutyrate · Isobutyl cinnamate · 6-Hydroxydihydrotheaspirane · Tributyl acetylcitrate · Dihydrocarvyl acetate
Citronellyl anthranilate FAQ
Is citronellyl anthranilate FEMA GRAS?
Yes. The FEMA Expert Panel lists citronellyl anthranilate as GRAS under FEMA number 4086. It is also codified at 21 CFR 172.515.
What are the FEMA and CAS numbers for citronellyl anthranilate?
Citronellyl anthranilate is FEMA 4086, CAS 68555-57-7. FEMA files it in the fruity flavor category.
Does citronellyl anthranilate count as natural in the US and the EU?
Citronellyl anthranilate occurs in nature, so the label depends on the route: citronellyl anthranilate won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized citronellyl anthranilate is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic citronellyl anthranilate identical-to-natural.
Is citronellyl anthranilate approved in the EU?
No EU FL number is on file for citronellyl anthranilate. It has a JECFA evaluation (JECFA 1539), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.
Has JECFA evaluated citronellyl anthranilate?
Yes. JECFA number 1539, evaluated at the 65th meeting in 2005. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.
How is citronellyl anthranilate described, and where does it show up?
Flavorists describe citronellyl anthranilate as sweet, fruity, floral, citrus, berry. It is used in beverage, confection, fruit flavors, personal care and aromatherapy.
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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as CITRONELLYL ANTHRANILATE under CAS 68555-57-7 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.