Flavor ingredient regulatory record

Isoamyl cinnamate

Isoamyl cinnamate is an ester in the fruity family, FEMA GRAS under FEMA number 2063 (CAS 7779-65-9). Its odor is sweet, fruity, banana, floral, cinnamon.

FEMA
2063
CAS
7779-65-9
JECFA
665
EU FL
09.742
Formula
C14H18O2
EC
231-931-2

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 7779-65-9.

Structure

2D structure of Isoamyl cinnamate
Structure of Isoamyl cinnamate, C14H18O2. Drawn from the canonical SMILES.

Identity

IUPAC name 3-methylbutyl (E)-3-phenylprop-2-enoate
CAS number 7779-65-9
FEMA number 2063
Molecular formula C14H18O2
Molecular weight 218.3 g/mol
SMILES CC(C)CCOC(=O)/C=C/c1ccccc1
InChIKey JFHCDEYLWGVZMX-CMDGGOBGSA-N
PubChem CID 5273467
EC number 231-931-2
FDA UNII AB60R20S7J
EPA DTXSID DTXSID4025454
Chemical class Ester
Boiling point 310 °C
Flash point 100 °C

Also known as: 2-Propenoic acid, 3-phenyl-, 3-methylbutyl ester, Cinnamic acid, isopentyl ester, Isopentyl alcohol, cinnamate, isopentyl cinnamate, isopentyl alcohol, cinnamate, cinnamic acid, isopentyl ester, 2-propenoic acid, 3-phenyl-, 3-methylbutyl ester, isopentyl 3-phenylacrylate, 3-methylbutyl (e)-3-phenylprop-2-enoate, 3-methylbutyl (2e)-3-phenylprop-2-enoate, isoamyl beta-phenylacrylate, isoamyl 3-phenyl propenoate.

Can Isoamyl cinnamate be labeled natural?

The process decides for isoamyl cinnamate. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic isoamyl cinnamate is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic isoamyl cinnamate identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Isoamyl cinnamate is FEMA GRAS under FEMA number 2063. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 09.742, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 665, evaluated at the 55th meeting in 2000. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Isoamyl cinnamate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 7779-65-9, where EPA names it 2-Propenoic acid, 3-phenyl-, 3-methylbutyl ester.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, fruity, banana, floral, cinnamon.

Where it is used

Isoamyl cinnamate is used in beverage, confection, fruit flavors, baked goods and ice cream, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Isoamyl cinnamate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Isobutyl cinnamate219384%In nature
Isoamyl phenylacetate208182%In nature
Cyclohexyl cinnamate235282%In nature
Phenethyl cinnamate286381%In nature
Propyl cinnamate293880%In nature

More esters in this index

l-Menthyl butyrate · trans-3-Hexenyl formate · 3-Oxododecanoic acid glyceride · Benzyl levulinate · Propyleneglycol dibutyrate · Allyl phenoxyacetate

Isoamyl cinnamate FAQ

Is isoamyl cinnamate on the FEMA GRAS list?

It is. FEMA number 2063 covers isoamyl cinnamate. The Code of Federal Regulations lists it at 21 CFR 172.515.

What is the FEMA number for isoamyl cinnamate?

The FEMA number for isoamyl cinnamate is 2063 and its CAS registry number is 7779-65-9. Its flavor category is fruity.

What is isoamyl cinnamate used for?

Isoamyl cinnamate is described as sweet, fruity, banana, floral, cinnamon. It shows up in beverage, confection, fruit flavors, baked goods and ice cream.

What did JECFA conclude about isoamyl cinnamate?

JECFA evaluated isoamyl cinnamate at the 55th meeting in 2000 under JECFA number 665. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Is isoamyl cinnamate approved in the EU?

Yes. FL 09.742 is the Union List entry for isoamyl cinnamate, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Is isoamyl cinnamate natural or artificial?

Nature makes isoamyl cinnamate, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial isoamyl cinnamate, same molecule. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ISOAMYL CINNAMATE under CAS 7779-65-9 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.