Flavor ingredient regulatory record

Menthyl propionate

Menthyl propionate is an ester in the fruity family, FEMA GRAS under FEMA number 4510 (CAS 86014-82-6). Its odor is sweet, fruity, minty, tropical, refreshing.

FEMA
4510
CAS
86014-82-6
JECFA
2247
Formula
C13H24O2

GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 86014-82-6.

Structure

2D structure of Menthyl propionate
Structure of Menthyl propionate, C13H24O2. Drawn from the canonical SMILES.

Identity

IUPAC name (5-methyl-2-propan-2-ylcyclohexyl) propanoate
CAS number 86014-82-6
FEMA number 4510
Molecular formula C13H24O2
Molecular weight 212.33 g/mol
SMILES CCC(=O)OC1CC(C)CCC1C(C)C
InChIKey PELLUIPPBKHUAB-UHFFFAOYSA-N
PubChem CID 95384
Chemical class Ester
Flash point 97 °C

Also known as: Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 1-propanoate, Cyclohexanol, 5-methyl-2-(1-methylethyl)-, propanoate, Menthol, propionate, Propionic acid, p-menth-3-yl ester, d-isomenthyl propionate, menthylpropionat, 5-methyl-2-(propan-2-yl)cyclohexyl propanoate, (2-isopropyl-5-methyl-cyclohexyl) propanoate, db-246513, cyclohexanol, 5-methyl-2-(1-methylethyl)-, 1-propanoate, (1s-(1alpha,2beta,5beta))-2-(isopropyl)-5-methylcyclohexyl propionate.

Can Menthyl propionate be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

Menthyl propionate is FEMA GRAS under FEMA number 4510. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

No EU FL number is on file for Menthyl propionate. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.

JECFA (WHO / FAO)

JECFA number 2247, evaluated at the 86th meeting in 2018. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, minty, tropical, refreshing.

Taste: Sweet, fruity, minty.

Where it is used

Menthyl propionate is used in beverage, confection, fruit flavors, ice cream and candies, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Menthyl propionate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
l-Menthyl butyrate452494%Not determined
Menthyl acetate266888%In nature
Menthyl valerate415688%In nature
Menthyl isovalerate266986%In nature

More esters in this index

Allyl cyclohexane butyrate · Allyl cinnamate · Ethyl Caprylate · cis-3-Hexenyl acetate · Ethyl 2-methyl-4-pentenoate · 3-Mercapto-3-methylbutyl formate

Menthyl propionate FAQ

Does menthyl propionate have FEMA GRAS status?

Menthyl propionate holds FEMA GRAS status under FEMA number 4510. It is also codified at 21 CFR 172.515.

How do I cite menthyl propionate by FEMA or CAS number?

Cite menthyl propionate as FEMA 4510 or CAS 86014-82-6; both point to the same entry. FEMA files it in the fruity flavor category.

Is menthyl propionate approved in the EU?

No EU FL number is on file for menthyl propionate. It has a JECFA evaluation (JECFA 2247), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.

Has JECFA evaluated menthyl propionate?

Yes. JECFA number 2247, evaluated at the 86th meeting in 2018. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

What does menthyl propionate smell and taste like, and where is it used?

The odor of menthyl propionate is sweet, fruity, minty, tropical, refreshing. On the palate it is sweet, fruity, minty. Typical uses are beverage, confection, fruit flavors, ice cream and candies.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as MENTHYL PROPIONATE under CAS 86014-82-6 and carries its FEMA number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.