Flavor ingredient regulatory record
Vanillin erythro- & threo-butan-2,3-diol acetal
Vanillin erythro- & threo-butan-2,3-diol acetal is an acetal in the vanilla family, FEMA GRAS under FEMA number 4023 (CAS 63253-24-7). Its odor is sweet, creamy, vanilla, floral, buttery.
- FEMA
- 4023
- CAS
- 63253-24-7
- JECFA
- 960
- EU FL
- 06.132
- Formula
- C12H16O4
GRAS status: FEMA GRAS, publication 20. Recorded by FDA in the Substances Added to Food inventory under CAS 63253-24-7.
Structure
Identity
Also known as: Phenol, 4-(4,5-dimethyl-1,3-dioxolan-2-yl)-2-methoxy-, 4-(4,5-Dimethyl-1,3-dioxolan-2-yl)-2-methoxyphenol, Vanillin butane-2,3-diol acetal, 4-(4,5-dimethyl-1,3-dioxolan-2-yl)-2-methoxyphenol, vanillin 1,2-butylene glycol acetal, vanillin butane-2,3-diol acetal, vanillin 2,3-butanediol acetal, phenol, 4-(4,5-dimethyl-1,3-dioxolan-2-yl)-2-methoxy-, vanillin 2,3-butylene glycol acetal, vanillin erythro-and threo-butan-2,3-diol acetal, vanillin erythro-and threo-butan-2,3-diol acetal [fhfi], vanillin erythro- and threo-butan-2,3-diol acetal.
Can Vanillin erythro- & threo-butan-2,3-diol acetal be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
Vanillin erythro- & threo-butan-2,3-diol acetal is FEMA GRAS under FEMA number 4023. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 06.132, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 960.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Sweet, creamy, vanilla, floral, buttery.
Taste: Sweet, smooth, rich.
Where it is used
Vanillin erythro- & threo-butan-2,3-diol acetal is used in beverage, confection, bakery and dairy, typically as a vanilla note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Vanillin erythro- & threo-butan-2,3-diol acetal by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Vanillin propylene glycol acetal | 3905 | 91% | In nature |
| Ethyl vanillin propylene glycol acetal | 3838 | 84% | In nature |
| Vanillyl ethyl ether | 3815 | 74% | In nature |
| Vanillin 3-(l-menthoxy)propane-1,2-diol acetal | 3904 | 69% | In nature |
| Piperonal propyleneglycol acetal | 4622 | 69% | Not determined |
More acetals in this index
Vanillin propylene glycol acetal · Vanillin 3-(l-menthoxy)propane-1,2-diol acetal · Ethyl vanillin propylene glycol acetal · Acetaldehyde 1,3-octadiol acetal · Hydroxycitronellal dimethyl acetal · Acetaldehyde diisoamyl acetal
Vanillin erythro- & threo-butan-2,3-diol acetal FAQ
Is Vanillin erythro- & threo-butan-2,3-diol acetal FEMA GRAS?
Yes. The FEMA Expert Panel lists Vanillin erythro- & threo-butan-2,3-diol acetal as GRAS under FEMA number 4023. The Code of Federal Regulations lists it at 21 CFR 172.515.
What are the FEMA and CAS numbers for Vanillin erythro- & threo-butan-2,3-diol acetal?
Vanillin erythro- & threo-butan-2,3-diol acetal is FEMA 4023, CAS 63253-24-7. Its flavor category is vanilla.
How is Vanillin erythro- & threo-butan-2,3-diol acetal described, and where does it show up?
Flavorists describe Vanillin erythro- & threo-butan-2,3-diol acetal as sweet, creamy, vanilla, floral, buttery. On the palate it is sweet, smooth, rich. It is used in beverage, confection, bakery and dairy.
What did JECFA conclude about Vanillin erythro- & threo-butan-2,3-diol acetal?
JECFA evaluated Vanillin erythro- & threo-butan-2,3-diol acetal under JECFA number 960.
Is Vanillin erythro- & threo-butan-2,3-diol acetal on the EU Union List?
Yes. FL 06.132 is the Union List entry for Vanillin erythro- & threo-butan-2,3-diol acetal, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as VANILLIN 1,2-BUTYLENE GLYCOL ACETAL under CAS 63253-24-7 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.