Flavor ingredient regulatory record

2-Hexylpyridine

2-Hexylpyridine is a pyridine in the fruity family, FEMA GRAS under FEMA number 4948 (CAS 1129-69-7). Its odor is earthy, nutty, green, woody, slightly sweet.

FEMA
4948
CAS
1129-69-7
EU FL
14.117
Formula
C11H17N
EC
214-454-4

GRAS status: FEMA GRAS. Source: FEMA Flavor Ingredient Library.

Structure

2D structure of 2-Hexylpyridine
Structure of 2-Hexylpyridine, C11H17N. Drawn from the canonical SMILES.

Identity

IUPAC name 2-hexylpyridine
CAS number 1129-69-7
FEMA number 4948
Molecular formula C11H17N
Molecular weight 163.26 g/mol
SMILES CCCCCCc1ccccn1
InChIKey NZLJDTKLZIMONR-UHFFFAOYSA-N
PubChem CID 70797
EC number 214-454-4
FDA UNII 64D57S7HGV
EPA DTXSID DTXSID10150207
Chemical class Pyridine
Boiling point 100 °C
Flash point 33 °C

Also known as: Pyridine, 2-hexyl-, 2-(n-Hexyl)pyridine, pyridine, 2-hexyl-, 2-(n-hexyl)pyridine, ai3-24115, pyridine, 2-(n-hexyl)-, 2-c6h13(c-c5h4n), 5-20-06-00161 (beilstein handbook reference), 2-n-hexylpyridine, 2-hexyl-pyridine, as-56684, db-021154.

Can 2-Hexylpyridine be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

2-Hexylpyridine is FEMA GRAS under FEMA number 4948. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 14.117, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

2-Hexylpyridine has not been evaluated by JECFA as a flavouring agent, or no evaluation is on file.

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Earthy, nutty, green, woody, slightly sweet.

Where it is used

2-Hexylpyridine is used in beverage, savory dishes, seasonings and snacks, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 2-Hexylpyridine by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
2-Pentylpyridine338394%In nature
Benzyl butyl ether213974%In nature
Cyclohexylmethylpyrazine363170%In nature
2-Heptylfuran340165%In nature
2-(3-Phenylpropyl)pyridine375165%In nature

More pyridines in this index

2-Acetyl-4-isopropenylpyridine · 2-Pentylpyridine · 2-Propylpyridine · 3-Isobutylpyridine · 2,4-Dimethylpyridine · 2-Isobutylpyridine

2-Hexylpyridine FAQ

Does 2-Hexylpyridine have FEMA GRAS status?

2-Hexylpyridine holds FEMA GRAS status under FEMA number 4948. It is also codified at 21 CFR 172.515.

How do I cite 2-Hexylpyridine by FEMA or CAS number?

Cite 2-Hexylpyridine as FEMA 4948 or CAS 1129-69-7; both point to the same entry. FEMA files it in the fruity flavor category.

Can 2-Hexylpyridine be used in the EU and UK?

2-Hexylpyridine is on the EU Union List of flavouring substances as FL 14.117 (Annex I Part A) under Regulation 1334/2008.

What does 2-Hexylpyridine smell and taste like, and where is it used?

The odor of 2-Hexylpyridine is earthy, nutty, green, woody, slightly sweet. Typical uses are beverage, savory dishes, seasonings and snacks.

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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification

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Screened against FEMA GRAS, 21 CFR and EU rules as you build. Free to start.

Sources and attribution. The FEMA number and GRAS status on this page name a conclusion reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States. FDA does not list this substance by FEMA number in its Substances Added to Food inventory. Its identity is attested by EU Union List of flavouring substances, matched on CAS 1129-69-7.

FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.