Flavor ingredient regulatory record

Ethyl 3-(furfurylthio)propionate

Ethyl 3-(furfurylthio)propionate is an ester in the fruity family, FEMA GRAS under FEMA number 3674 (CAS 94278-27-0). Its odor is sweet, fruity, caramel, nutty, estery.

FEMA
3674
CAS
94278-27-0
JECFA
1088
EU FL
13.093
Formula
C10H14O3S
EC
304-716-7

GRAS status: FEMA GRAS, publication 13. Recorded by FDA in the Substances Added to Food inventory under CAS 94278-27-0.

Structure

2D structure of Ethyl 3-(furfurylthio)propionate
Structure of Ethyl 3-(furfurylthio)propionate, C10H14O3S. Drawn from the canonical SMILES.

Identity

IUPAC name ethyl 3-(furan-2-ylmethylsulfanyl)propanoate
CAS number 94278-27-0
FEMA number 3674
Molecular formula C10H14O3S
Molecular weight 214.29 g/mol
SMILES CCOC(=O)CCSCc1ccco1
InChIKey ZKCVVCLCYIXCOD-UHFFFAOYSA-N
PubChem CID 556940
EC number 304-716-7
FDA UNII E9G0NGH9PL
EPA DTXSID DTXSID30241388
Chemical class Ester
Boiling point 120 °C
Flash point 44 °C

Also known as: Propanoic acid, 3-[(2-furanylmethyl)thio]-, ethyl ester, Ethyl 3-[(2-furanylmethyl)thio]propanoate, ethyl 3-[(2-furanylmethyl)thio]propanoate, ethyl 3-((2-furanylmethyl)thio)propanoate, ethyl beta-furfuryl-alpha-thiopropionate, ethyl 3-(furfurylthio) propionate, ethyl 3-(furfurylthio)propionate [fhfi], ethyl 3-[(furan-2-ylmethyl)sulfanyl]propanoate, ethyl .beta.-furfuryl-.alpha.-thiopropionate, ethyl 3-((furan-2-ylmethyl)sulfanyl)propanoate, ethyl 3-(2-furylmethylsulfanyl)propanoate, ethyl 3-(furan-2-ylmethylsulfanyl)propanoate.

Can Ethyl 3-(furfurylthio)propionate be labeled natural?

Since ethyl 3-(furfurylthio)propionate is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when ethyl 3-(furfurylthio)propionate is synthesized. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Ethyl 3-(furfurylthio)propionate is FEMA GRAS under FEMA number 3674. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 13.093, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1088, evaluated at the 64th meeting in 2005. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, caramel, nutty, estery.

Where it is used

Ethyl 3-(furfurylthio)propionate is used in beverage, confection, fruit flavors, bakery and snacks, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Ethyl 3-(furfurylthio)propionate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Propyl furfuryl disulfide397971%Not determined
Furfuryl pentanoate339771%In nature
O-Ethyl-S-(2-furylmethyl) thiocarbonate404369%In nature
2,2'-(Dithiodimethylene)difuran314665%In nature
2,5-Dimethyl-3-thiofuroylfuran348165%Not determined

More esters in this index

Ethyl N-methylanthranilate · Citronellyl anthranilate · Isobornyl acetate · Propyleneglycol mono-2-methylbutyrate · 2-Acetoxy-3-butanone · (+/-)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, ethyl ester

Ethyl 3-(furfurylthio)propionate FAQ

Is ethyl 3-(furfurylthio)propionate on the FEMA GRAS list?

It is. FEMA number 3674 covers ethyl 3-(furfurylthio)propionate. It is also codified at 21 CFR 172.515.

What is the FEMA number for ethyl 3-(furfurylthio)propionate?

The FEMA number for ethyl 3-(furfurylthio)propionate is 3674 and its CAS registry number is 94278-27-0. FEMA files it in the fruity flavor category.

Is ethyl 3-(furfurylthio)propionate natural or artificial?

Ethyl 3-(furfurylthio)propionate occurs in nature, so the label depends on the route: ethyl 3-(furfurylthio)propionate won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized ethyl 3-(furfurylthio)propionate is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

Is ethyl 3-(furfurylthio)propionate approved in the EU?

Ethyl 3-(furfurylthio)propionate is on the EU Union List of flavouring substances as FL 13.093 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated ethyl 3-(furfurylthio)propionate?

Yes. JECFA number 1088, evaluated at the 64th meeting in 2005. Conclusion: no safety concern at current levels of intake.

What is ethyl 3-(furfurylthio)propionate used for?

Ethyl 3-(furfurylthio)propionate is described as sweet, fruity, caramel, nutty, estery. It shows up in beverage, confection, fruit flavors, bakery and snacks.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ETHYL 3-(FURFURYLTHIO) PROPIONATE under CAS 94278-27-0 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.