Flavor ingredient regulatory record
Triethylamine
Triethylamine is an amine in the earthy family, FEMA GRAS under FEMA number 4246 (CAS 121-44-8). Its odor is fishy, ammonia-like, pungent, sharp.
- FEMA
- 4246
- CAS
- 121-44-8
- JECFA
- 1611
- EU FL
- 11.023
- Formula
- C6H15N
- EC
- 204-469-4
GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 121-44-8.
Structure
Identity
Also known as: Ethanamine, N,N-diethyl-, N,N-Diethylethanamine, (Diethylamino)ethane, TEA, N,N,N-Triethylamine, LE 11-5RG, ATB 0489, T 0886, Triethyl amine, n,n-diethylethanamine, (diethylamino)ethane, ethanamine, n,n-diethyl-.
Can Triethylamine be labeled natural?
Since triethylamine is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when triethylamine is synthesized. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic triethylamine identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
Triethylamine is FEMA GRAS under FEMA number 4246. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 11.023, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1611, evaluated at the 65th meeting in 2005. No safety concern (conditional) at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Triethylamine appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 121-44-8, where EPA names it Ethanamine, N,N-diethyl-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Fishy, ammonia-like, pungent, sharp.
Taste: Bitter, pungent, chemical.
Where it is used
Triethylamine is used in flavor masking, food additives and chemical synthesis, typically as a earthy note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Triethylamine by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 1,1-Dimethoxyethane | 3426 | 85% | In nature |
| Tripropylamine | 4247 | 85% | Not determined |
| 2-Ethylbutyraldehyde | 2426 | 75% | In nature |
| Trimethylamine | 3241 | 71% | In nature |
| sec-Butyl ethyl ether | 3131 | 54% | In nature |
More amines in this index
Ethylamine · Isobutylamine · Pyrrolidine · Isopropylamine · Propylamine · Butylamine
Triethylamine FAQ
Does triethylamine have FEMA GRAS status?
Triethylamine holds FEMA GRAS status under FEMA number 4246. It is also codified at 21 CFR 172.515.
How do I cite triethylamine by FEMA or CAS number?
Cite triethylamine as FEMA 4246 or CAS 121-44-8; both point to the same entry. FEMA files it in the earthy flavor category.
Can triethylamine be labeled a natural flavor?
Triethylamine occurs in nature, so the label depends on the route: triethylamine won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized triethylamine is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
Can triethylamine be used in the EU and UK?
Triethylamine is on the EU Union List of flavouring substances as FL 11.023 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated triethylamine?
Yes. JECFA number 1611, evaluated at the 65th meeting in 2005. Conclusion: No safety concern (conditional) at current levels of intake when used as a flavouring agent.
What does triethylamine smell and taste like, and where is it used?
The odor of triethylamine is fishy, ammonia-like, pungent, sharp. On the palate it is bitter, pungent, chemical. Typical uses are flavor masking, food additives and chemical synthesis.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as TRIETHYLAMINE under CAS 121-44-8 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.