Flavor ingredient regulatory record
(+/-) N,N-Dimethyl menthyl succinamide
(+/-) N,N-Dimethyl menthyl succinamide is an amide in the mint family, FEMA GRAS under FEMA number 4230 (CAS 544714-08-1). Its odor is minty, fresh, herbal, sweet.
- FEMA
- 4230
- CAS
- 544714-08-1
- JECFA
- 1602
- EU FL
- 16.092
- Formula
- C16H29NO3
GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 544714-08-1.
Structure
Identity
Also known as: Butanoic acid, 4-(dimethylamino)-4-oxo-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl 4-(dimethylamino)-4-oxobutanoate, Menthyl-N,N-dimethylsuccinamate, FEMA 4230, (1r,2s,5r)-5-methyl-2-(1-methylethyl)cyclohexyl 4-(dimethylamino)-4-oxobutanoate, n,n-dimethyl menthyl succinamide, n,n-dimethylmenthylsuccinamide, n,n-dimethyl n'-(3-menthyl) succinamide, n,n-dimethyl menthyl succinamide [fifh], ((1r,2s,5r)-2-isopropyl-5-methyl-cyclohexyl) 4-(dimethylamino)-4-oxo-butanoate, butanoic acid, 4-(dimethylamino)-4-oxo-, (1r,2s,5r)-5-methyl-2-(1-methylethyl)cyclohexyl ester, [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] 4-(dimethylamino)-4-oxobutanoate.
Can (+/-) N,N-Dimethyl menthyl succinamide be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
(+/-) N,N-Dimethyl menthyl succinamide is FEMA GRAS under FEMA number 4230. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 16.092, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1602, evaluated at the 65th meeting in 2005. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Minty, fresh, herbal, sweet.
Where it is used
(+/-) N,N-Dimethyl menthyl succinamide is used in beverage, confection, oral care and flavoring, typically as a mint note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to (+/-) N,N-Dimethyl menthyl succinamide by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| mono-Menthyl succinate | 3810 | 74% | In nature |
| D,L-Menthol(+/-)-propylene glycol carbonate | 3992 | 74% | In nature |
| (-)-Menthol 1- and 2-propylene glycol carbonate | 3806 | 72% | Not determined |
| N-[(Ethoxycarbonyl)methyl)-p-menthane-3-carboxamide | 4309 | 72% | Not determined |
| (E,Z)-Phytyl acetate | 4197 | 68% | In nature |
More amides in this index
N-p-Benzene acetonitrile-menthane-carboxamide · N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide · N1-(2-Methoxy-4-methylbenzyl)-N2-(2-(pyridin-2-yl)ethyl)oxalamide · WS-3 · N1-(2,4-Dimethoxybenzyl)-N2-(2-(pyridin-2-yl)ethyl)oxalamide · N-(2-Methylcyclohexyl)-2,3,4,5,6-pentafluorobenzamide
(+/-) N,N-Dimethyl menthyl succinamide FAQ
Is (+/-) N,N-Dimethyl menthyl succinamide FEMA GRAS?
Yes. The FEMA Expert Panel lists (+/-) N,N-Dimethyl menthyl succinamide as GRAS under FEMA number 4230. It is also codified at 21 CFR 172.515.
What are the FEMA and CAS numbers for (+/-) N,N-Dimethyl menthyl succinamide?
(+/-) N,N-Dimethyl menthyl succinamide is FEMA 4230, CAS 544714-08-1. FEMA files it in the mint flavor category.
Is (+/-) N,N-Dimethyl menthyl succinamide on the EU Union List?
(+/-) N,N-Dimethyl menthyl succinamide is on the EU Union List of flavouring substances as FL 16.092 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated (+/-) N,N-Dimethyl menthyl succinamide?
Yes. JECFA number 1602, evaluated at the 65th meeting in 2005. Conclusion: no safety concern at current levels of intake.
How is (+/-) N,N-Dimethyl menthyl succinamide described, and where does it show up?
Flavorists describe (+/-) N,N-Dimethyl menthyl succinamide as minty, fresh, herbal, sweet. It is used in beverage, confection, oral care and flavoring.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (+/-)-N,N-DIMETHYL MENTHYL SUCCINAMIDE under CAS 544714-08-1 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavor enhancer.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.